• Adult Clinical Trials: GYNECOLOGICAL

    RTOG 1203

    A Randomized Phase III Study of Standard vs. IMRP Pelvic Radiation for Post-Operative Treatment of Endometrial and Cervical Cancer (TIME-C).

    To determine if IMRT reduces acute gastrointestinal toxicity in the 5th week (after 23-25 fractions) of pelvic radiation as measured with EPIC.

    • Hysterectomy required, bilateral salpingo-oophorectomy at surgeon's discretion
    • Chest CT, MRI or PET-CT 90 days prior to registration
    • Positive or close margins (<3mm) are ineligible

    Treatment

    Arm I: IMRT pelvic radiation treatment 
    Arm II: 4-field pelvic radiation treatment