Adult Clinical Trials: GYNECOLOGICAL

RTOG 1203

A Randomized Phase III Study of Standard vs. IMRP Pelvic Radiation for Post-Operative Treatment of Endometrial and Cervical Cancer (TIME-C).

To determine if IMRT reduces acute gastrointestinal toxicity in the 5th week (after 23-25 fractions) of pelvic radiation as measured with EPIC.

  • Hysterectomy required, bilateral salpingo-oophorectomy at surgeon's discretion
  • Chest CT, MRI or PET-CT 90 days prior to registration
  • Positive or close margins (<3mm) are ineligible


Arm I: IMRT pelvic radiation treatment 
Arm II: 4-field pelvic radiation treatment